Living with Heart Failure and Obesity?
If you’ve been diagnosed with Heart Failure and are living with obesity, you may qualify for the Heart Failure clinical research study. We are studying whether it may help reduce the risk of serious heart failure-related complications.
Heart Failure Study Pre-Screening
Complete our secure pre-screening form. A member of our research team will contact you to discuss your eligibility.
participation requirements
Who We're Looking For
You May Qualify If You:
Adults who meet certain study requirements may qualify.
Are 18 years of age or older
Have heart failure with preserved or mildly reduced ejection fraction
Are living with obesity (BMI ≥30 kg/m²)
Are currently receiving treatment for heart failure
Are able to attend scheduled study visits
Additional eligibility requirements apply. A study team member will review your medical history to determine whether you qualify.
study benefit
Why Consider Participating?
Participation in clinical research is a personal decision. If you qualify, you may receive:
Study-Related Care
Receive protocol-required study visits, assessments, and procedures at no cost.
Heart Health Monitoring
Your health and heart-related measures will be monitored throughout the study.
Experienced Research Team
Receive study care from an experienced cardiovascular research team.
Help Advance Medical Research
Your participation may help researchers better understand future approaches to heart failure and obesity.
ELIGIBILITY CRITERIA
Are You at Increased Risk for Heart Failure?
Answer a few quick questions to see if this study may be right for you.
You May Qualify If:
- You are 40 years of age or older
- You have been diagnosed with Type 2 Diabetes
- You have High Blood Pressure
- You have a history of Heart Disease or Cardiovascular Disease
- You have not been diagnosed with symptomatic heart failure
You May Not Qualify If:
- You are under 40 years of age
- You have Type 1 Diabetes
- You have already been diagnosed with symptomatic heart failure
- Your medical history does not meet the study requirements
Note: Completing the pre-screening form does not guarantee eligibility. Our research team will review your information and contact you to discuss the next steps.
About the Heart Failure and Obesity Clinical Research Study
Researchers are studying Maridebart Cafraglutide in adults living with heart failure with preserved or mildly reduced ejection fraction (HFpEF or HFmrEF) and obesity.
The study is designed to evaluate the safety and effectiveness of the study medication and its potential effects on important heart failure-related health outcomes.
During the first part of the study, participants may receive either Maridebart Cafraglutide or placebo.
This is a clinical research study. Participation does not guarantee a personal benefit, and the study team will explain the potential risks and benefits before you decide whether to participate.

Why Heart Failure and Obesity Research Matters:Â
Understanding Heart Failure & Obesity
- Heart failure and obesity can occur together and may create additional health challenges.
- Many people continue experiencing symptoms despite current treatment.
People living with heart failure may experience symptoms that affect everyday activities, while obesity can add to the overall cardiovascular burden.
Researchers are studying new approaches to better understand how potential treatments may affect people living with both conditions.
Every Participant Helps Advance Research
Your participation may help researchers learn more about heart failure and obesity and contribute to future cardiovascular research.
About Dr. Ayim Djamson
Dr. Ayim Djamson is a board-certified cardiologist with more than 20 years of clinical research experience. He has served as Principal Investigator on over 50 Phase II–IV clinical trials, helping advance new treatments for heart-related conditions.
Board-Certified Cardiologist
Dr. Ayim Djamson
MD, FACC
Cardiovascular Research
Leading heart health clinical trials
Patient-Centered Care
Dedicated to safe, compassionate research
What to Expect
Your Journey Through the Study
Step 1
Complete the online pre-screening form.
Step 2
Speak with a member of our research team.
Step 3
Schedule a screening visit if you appear eligible.
Step 4
The study team will determine whether you qualify for enrollment.
Take the First Step Today
Call (240) 685-2078 or email info@metresearch.org to speak with our research team and learn if you may qualify for this study.Â
Address
10756 Rhode Island
Avenue Beltsville, MD
20705
Hours
Monday – Friday: 9:00 AM – 5:30 PM
Saturday – Sunday: Closed
Transportation
Appointments:
(240) 685-2078
info@metresearch.org
Help Shape The Future of Heart Health? Health?
If you’re living with heart failure and obesity, you may qualify for this clinical research study. Complete our confidential per-screening questionnaire to see whether you may be eligible.
Frequently Asked Questions
What is this study about?
This is a Phase 3 clinical research study evaluating Maridebart Cafraglutide in adults living with heart failure and obesity.
Who may qualify?
Adults with HFpEF or HFmrEF, obesity, and other required study criteria may qualify.
Is the study medication approved?
Maridebart cafraglutide is being studied as part of clinical research. The study team can provide more information about its current status.
Will I continue my current heart failure treatment?
Your study physician will review your current medications and determine how they fit with the study requirements.
Will I receive maridebart cafraglutide?
During the blinded portion of the study, participants are randomly assigned to receive either maridebart cafraglutide or placebo.
How long does participation last?
During the blinded portion of the study, participants are randomly assigned to receive either maridebart cafraglutide or placebo.
How often are study visits?
Participants attend scheduled visits for study medication, health assessments, and safety monitoring.
Is there a cost to participate?
Study-related care and required study assessments are provided at no cost to participants.
Is participation voluntary?
Study-related care and required study assessments are provided at no cost to participants.
Will my information be kept confidential?
Your personal and medical information will be handled according to applicable privacy requirements.